Herantis Pharma has announced that its novel drug candidate, Cerebral Dopamine Neurotrophic Factor (CDNF) for the treatment of Parkinson’s disease (PD), has successfully achieved its primary endpoint of safety and tolerability in a 12 month Phase I-II study in patients with moderate disease.

CDNF-studieläkemedlet administreras in i hjärnan via katetrar. Mer information om studien fås från TreatER-studiens nätsida: https://treater.eu/sv/clinical-study/.

The intranasal administration route of CDNF is an important program for Herantis to maximize the chances of success for CDNF in brain disorders. We are excited to evaluate the Nanoform technology as part of this initiative; and we look forward to what this partnership will bring. Herantis Pharma is launching a development program for non-invasive cerebral dopamine neurotrophic factor (CDNF) as a treatment candidate for patients with Parkinson’s disease, the company recently announced. CDNF is a synthetic neurotrophic factor, or protein that helps nerve cells survive.

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CDNF biological therapy that acts on the proteostatic mechanisms of disease for the treatment of Parkinson’s disease and other neurodegenerative diseases, and ii. Herantis Pharma Plc is an innovative drug development company looking to break the boundaries of standard therapeutic approaches. Our regenerative medicine drug candidates include i. CDNF biological therapy that acts on the proteostatic mechanisms of disease for the treatment of Parkinson’s disease and other neurodegenerative diseases, and ii.

Herantis Pharma Oyj: NOTICE TO CONVENE HERANTIS PHARMA PLC'S ANNUAL GENERAL MEETING OF SHAREHOLDERS 23 Mar 2021 / Press release; Livestreamed Seminar Today - ABGSC Investor Day 9 March 9 Mar 2021 / Article; Herantis Pharma - H2’20 Report 3 Mar 2021 / Analys

Based on internationally recognized science, Herantis’ drug development pipeline targets breakthroughs in diseases with unmet clinical need. We aim to develop our products through clinical proof-of-concept and, where considered appropriate, to partner with large pharmaceutical or biotech companies for late-stage development and commercialization. Herantis Pharma Plc is an innovative drug development company looking to break the boundaries of standard therapeutic approaches. Our regenerative medicine drug candidates include i.

2017-10-02

The ongoing study aims to evaluate the safety and tolerability of CDNF delivered directly to the brain in 17 people with advanced Parkinson's. 2019-08-28 Herantis also announced today the next step for the CDNF program with the planning of a Phase 2 study with a longer treatment period that will assess the efficacy of CDNF in earlier-stage, well-characterized Parkinson’s patients.

Herantis is taking this natural ability and harnessing it as a treatment for neurodegenerative disease. CDNF is a novel neuroprotective and neurorestorative factor highly distinct from conventional neurotrophic factors. An innovative drug candidate for the treatment of neurodegenerative diseases, CDNF, is patented internationally by Herantis. CDNF – a biological protein – is Herantis’ lead program and a clinical stage asset; and xCDNF – a synthetic peptide version of CDNF – is Herantis’ follow-on program.
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2020-02-25 Herantis Pharma has published initial results from a phase 1/2 study of an experimental protective protein called CDNF which may hold potential to slow, stop or reverse Parkinson's. The ongoing study aims to evaluate the safety and tolerability of CDNF delivered directly to the brain in 17 people with advanced Parkinson's.

En känd utmaning i läkemedelsvärlden vid behandling av  Teknisk analys Herantis Pharma (HRNTS). CDNF for Parkinson's disease, Lymfactin for secondary lymphedema, CDNF for Amyotrophic lateral sclerosis and  Herantis Pharma Oyj: Herantis Pharma to focus on CDNF and xCDNF programs. 29.3.2021 Digitalous · Legendaarisesta scifi-tähdestä tehtiin  (CDNF) infusion till patienter med PS av måttlig svårighetsgrad. Studien har fått EU stöd och sponsorn är Herantis Pharma (https://treater.eu; ClinicalTrials.
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Herantis is currently exploring other less invasive, more patient-friendly ways to deliver CDNF to patients. This includes certain parenteral routes and intranasal administration. In addition to Parkinson’s disease, CDNF has shown potent neuroprotective and neurorestorative effects in preclinical models of several other neurodegenerative conditions.

Data reported for the first six months are preliminary in this first-in-human clinical study for this novel MOA drug class. Safety and tolerability have been confirmed but, interestingly, the early biological efficacy signals (seen on PET imaging) serve 2018-02-14 · Herantis Pharma opening recruitment in Parkinson's disease study in Helsinki and Lund based on favorable first CDNF safety assessment. Herantis Pharma Plc Company release 14 February 2018 at 9:00 am. 2017-09-27 · Herantis Pharma has initiated patient recruitment and consented first patient in CDNF study in Parkinson's disease. Herantis Pharma Plc Company release 27 Sep 2017 at 9:00 am Herantis Pharma är ett forskningsbolag. Idag innehas särskilt fokus mot behandling av ett flertal sjukdomar som Parkinsons sjukdom, skleros samt bröstcancer.